Associations of total and central fatness with carotid and femoral stiffness: analyses of the mediating role by adipokines, endothelial dysfunction and low-grade inflammation The Amsterdam Growth and Health Longitudinal Study
نویسندگان
چکیده
منابع مشابه
Endothelial dysfunction and low-grade inflammation are associated with greater arterial stiffness over a 6-year period.
Endothelial dysfunction and low-grade inflammation are associated with cardiovascular disease. Arterial stiffening plays an important role in cardiovascular disease and, thus, may be a mechanism through which endothelial dysfunction and/or low-grade inflammation lead to cardiovascular disease. We investigated the associations between, on the one hand, biomarkers of endothelial dysfunction (solu...
متن کاملCarotid stiffness in young adults: a life-course analysis of its early determinants: the Amsterdam Growth and Health Longitudinal Study.
Cardiovascular risk factors affecting arterial stiffness in adulthood may develop at different critical periods earlier in life. We examined whether the trajectories, from adolescence to young adulthood, of blood pressure, body fatness and fat distribution, blood lipids, cardiorespiratory fitness, and heart rate determined levels of arterial stiffness in young adults. We investigated 373 appare...
متن کاملThe metabolic syndrome, cardiopulmonary fitness, and subcutaneous trunk fat as independent determinants of arterial stiffness: the Amsterdam Growth and Health Longitudinal Study.
BACKGROUND The mechanisms that link the metabolic syndrome to increased cardiovascular risk are incompletely understood, especially in young people. We therefore examined whether the metabolic syndrome was associated with arterial stiffness and whether any such associations were independent of cardiopulmonary fitness and subcutaneous trunk fat. METHODS Cross-sectional analyses of data on 364 ...
متن کاملchapter 7 – vasomotion and adiponectin
Obesity-related microvascular dysfunction, including alterations in rhythmic changes in vascular diameter, socalled 'vasomotion', may be important in the clustering of obesity with other cardiovascular risk factors. Adipokines have been suggested to play a role in obesity-related vascular dysfunction. Alterations in vasomotion have been found using extreme body mass index (BMI) phenotypes. Whet...
متن کاملارتباط گرفتاری آترواسکلروتیک شرایین محیطی با درگیری پاتولوژیک قوس آئورت در بیماران تحت بایپس عروق کرونر قلبی
Background: A correlation between coronary artery disease (CAD) and atherosclerosis of peripheral arteries and the determination of noninvasive indexes for its existence and extent have been sought by many researchers. Some studies report that the intima-media thickness (IMT) of peripheral arteries could play this role. This study evaluated the correlation between the IMTs of common carotid and...
متن کامل